Pelacarsen sharply lowers a heart-risk marker but fails to prevent cardiovascular complications

Study the questions and tasks

Work through the material below, or start the interactive practice above to complete an attempt. Try the exercises before opening any answer or transcript sections, then use them to review your work.

Practice level

C2. Try this level if you can follow the instructions and understand most of the language; choose an earlier level if you need more support.

Question formats

Single choice

How to approach this practice

Use the surrounding sentence to identify the meaning and word form needed. Check which words naturally go together.

1. Question 1 · Single choice

   Choose one answer.

   In the article, what does “associated” mean in the sentence about Lp(a) and heart disease?

   1. Connected with or regarded as linked to something, without necessarily proving that it causes it.
   2. Proven to prevent
   3. Completely separate from
   4. Deliberately concealed from
   Check answers and explanations

   Answer

   Connected with or regarded as linked to something, without necessarily proving that it causes it.

   The word signals a link, without itself asserting causation.

2. Question 2 · Single choice

   Choose one answer.

   What does “persist” mean in the description of a risk despite healthy habits?

   1. To continue to exist or occur, especially despite efforts or conditions that might be expected to end it.
   2. Increase suddenly and briefly
   3. Be measured with precision
   4. Disappear without intervention
   Check answers and explanations

   Answer

   To continue to exist or occur, especially despite efforts or conditions that might be expected to end it.

   The risk continues despite conditions that might seem protective.

3. Question 3 · Single choice

   Choose one answer.

   In “elevated Lp(a),” what does “elevated” mean?

   1. Higher than what is usual, expected, or considered normal.
   2. Reduced through treatment
   3. Unrelated to any comparison
   4. Measured at regular intervals
   Check answers and explanations

   Answer

   Higher than what is usual, expected, or considered normal.

   It describes a level above the usual or expected range.

4. Question 4 · Single choice

   Choose one answer.

   What does “suppress” mean in the account of pelacarsen’s effect?

   1. To reduce or restrain the activity, expression, or level of something.
   2. Confirm the causal role of
   3. Replace with a different marker
   4. Make more widely available
   Check answers and explanations

   Answer

   To reduce or restrain the activity, expression, or level of something.

   The drug restrained or lowered the marker’s level.

5. Question 5 · Single choice

   Choose one answer.

   What does “corresponding” convey in “a corresponding reduction in complications”?

   1. Matching or directly related to something else in position, amount, or effect.
   2. Unexpectedly delayed
   3. Entirely independent
   4. Temporarily concealed
   Check answers and explanations

   Answer

   Matching or directly related to something else in position, amount, or effect.

   It describes a matching change in another measure.

6. Question 6 · Single choice

   Choose one answer.

   What does “distinction” refer to in the sentence “That distinction matters”?

   1. A meaningful difference between two things that may otherwise appear similar.
   2. An unverified estimate of quantity
   3. A formal medical qualification
   4. An outcome that exceeds expectations
   Check answers and explanations

   Answer

   A meaningful difference between two things that may otherwise appear similar.

   It points to a meaningful difference between related ideas.

7. Question 7 · Single choice

   Choose one answer.

   In the final paragraph, what does “insufficient” mean?

   1. Not enough in quantity, degree, or quality to meet a need or achieve an aim.
   2. Too costly to administer widely
   3. Unlikely to be measured accurately
   4. No longer associated with disease
   Check answers and explanations

   Answer

   Not enough in quantity, degree, or quality to meet a need or achieve an aim.

   The existing measures were not enough for those patients.

8. Question 8 · Single choice

   Choose one answer.

   What does “underscore” mean in the article’s concluding sentence?

   1. To emphasize the importance, seriousness, or truth of something.
   2. Resolve conclusively through evidence
   3. Reduce the strength of an argument
   4. Distinguish visually from surrounding text
   Check answers and explanations

   Answer

   To emphasize the importance, seriousness, or truth of something.

   The results emphasize the broader challenge described.

What to review next

Keep a short list of unfamiliar words with their meanings and example sentences. Practise recalling them later, then use them in a sentence of your own.

A focused practice result shows how you did on these tasks. Use several activities across skills to decide what to study next; one practice score does not certify an overall CEFR level.

Before you practise: a worked example

Read the whole sentence before choosing a word. Check both its meaning and the words it naturally combines with.

Please make an appointment before visiting the clinic.

Make an appointment is a natural word combination. Knowing a dictionary meaning alone may not tell you which verb fits.

This teaching example is separate from the scored questions. After your test, compare any mistakes with the explanation and revisit the topic before trying again.